Hwang, Meffert, Parsley, Tyler, Erway, Botkin et al. (2019) investigated how ADHD symptom severity was related to an impaired usage of brain regions that are implicated in response inhibition or sustained attention. Three results were revealed. treatmentHere was found a positive association among ADHD symptom severity related to the error rate of no-go trials that appeared infrequently. In addition, ADHD symptom severity exhibited a negative linear association with activation in the left insular cortex concerning no-go cues. Lastly, ADHD symptom severity revealed a quadratic association with activation in the left superior frontal cortex for low frequency trials.
Behavioral performance was also found to be impaired in ADHD, as reflected by enhanced error rates on low frequency no-go trials as well as shorter reaction times for go trials that were less frequent.
It is concluded that there are the same as well as separate neural impairments in response inhibition as found for the anterior insula as well as for sustained attention, found in the superior frontal cortex in ADHD patients (Hwang et al., 2019).
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